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Comprehensive evaluation of the physiological and functional adaptations induced by locomotor training in incomplete spinal cord injured subjects
Allan, DB (Mr). Conway, B (Prof). Granat, MH (Dr). Hassler, J (Mr). Hunt, KJ (Dr). 
University of Strathclyde
Categories : Clinical Initiative. Human. Outcome measures. Rehabilitation. 
Start date: August 2006
End Date: July 2009

As one of the groups that are taking part in Stage 2 of the Clinical Initiative, a scientist, clinician, physiotherapist and engineer are fine-tuning tests to monitor all aspects of spinal cord function as patients receive physiotherapy that involves assisted walking on a treadmill.

Accurate, reliable methods to assess small changes in spinal cord function are needed before we start to test any potential treatments in humans. In Stage 2 of the Clinical Initiative, researchers are refining a battery of tests that will be used to determine spinal cord function during clinical trials of potential therapies.

In this study, these tests will be assessed in patients with incomplete spinal cord injuries as they undergo a locomotor training program that involves repeated physiotherapy in which they are trained (with assisitance) to walk on a treadmill. This type of rehabilitation therapy is known to significantly improve mobility in patients with incomplete injuries, so it is an ideal situation in which to evaluate the sensitivity and usefulness of tests to determine changes in spinal cord function.

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